Sacral Chordoma

Skull base Chordoma

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Skull base chordoma

General things on skull base chordoma

35 % of all chordoma are located at the so-called clivus (see red area on the picture down at this page) at the base of the skull [2].

Prevalence and Incidence

Skull base chordoma are usually diagnosed at age 38 whereas sacral chordoma typically develop around the age of 60. [9,10]. In skull base chordoma both sexes show a similar incidence rate.

Display of the skull base

Histological variants

Three different histological types are differentiated: conventional, chondroid and

dedifferentiated chordoma [9].
Conventional chordoma per definition do not contain chondroid (chondroid chordoma) or mesenchymal (dedifferentiated chordoma) components.

Skull base, the clivus is displayed in red

(Taken from Wayne State University, School of Medicine)

Symptoms

The most common symptoms in skull base chordoma are headache and diplopia (one is seeing doubled images). Furthermore, depending on what nerval structures are affected there might be pain in the trigeminal region of the face for example or other pain / symptoms. hinzu.

Prognosis

Chondroid Chordoma, which are common at the skull base [9], have an average survival rate of 16 years whereas conventional chordoma are reported to be associated with an average survival of 4-7 years. The worst prognosis is for the dedifferentiated chordoma, which contain additional mesenchymal components and that are similar to sarcoma. The average survival rate for tose tumors is 6-12 months following diagnosis. These types of chordoma tend to frequently build recurrences and tend to metastasize. However, only 1,3% - 8% of all chordoma belong to this typ.

The 5-year survival rate is approximately 82% [10].

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		Skull base chordoma General things on skull base chordoma 35 % of all chordoma are located at the so-called clivus (see red area on the picture down at this page) at the base of the skull [2]. Prevalence and Incidence Skull base chordoma are usually diagnosed at age 38 whereas sacral chordoma typically develop around the age of 60. [9,10]. In skull base chordoma both sexes show a similar incidence rate. Display of the skull base Histological variants Three different histological types are differentiated: conventional, chondroid and dedifferentiated chordoma [9]. Conventional chordoma per definition do not contain chondroid (chondroid chordoma) or mesenchymal (dedifferentiated chordoma) components. Skull base, the clivus is displayed in red (Taken from Wayne State University, School of Medicine) Symptoms The most common symptoms in skull base chordoma are headache and diplopia (one is seeing doubled images). Furthermore, depending on what nerval structures are affected there might be pain in the trigeminal region of the face for example or other pain / symptoms. hinzu. Prognosis Chondroid Chordoma, which are common at the skull base [9], have an average survival rate of 16 years whereas conventional chordoma are reported to be associated with an average survival of 4-7 years. The worst prognosis is for the dedifferentiated chordoma, which contain additional mesenchymal components and that are similar to sarcoma. The average survival rate for tose tumors is 6-12 months following diagnosis. These types of chordoma tend to frequently build recurrences and tend to metastasize. However, only 1,3% - 8% of all chordoma belong to this typ. The 5-year survival rate is approximately 82% [10].

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